Stay Fit Moms Group

In the Indian regulatory framework, Ayurvedic products are categorized into two distinct types based on their formulation source.

• Classical (Shastriya) Formulations: These are medicines manufactured exactly as described in ancient authoritative texts (such as the Charaka Samhita or Sushruta Samhita). They are sold under their traditional names (e.g., Chyawanprash, Triphala Churna) and are not subject to individual patenting.

• Proprietary (Anubhavasidha) Products: Also known as "Patent & Proprietary" (P&P) medicines, these are unique formulations developed through independent research or clinical experience. While they use Ayurvedic ingredients, the specific ratios or combinations are owned by the manufacturer. By 2026, these products require rigorous proof of safety and efficacy for licensing.

By 2026, the clinical use of ACE inhibitors has expanded into preventative "precision medicine," where they are used to prevent structural damage to the heart and kidneys before symptoms fully manifest.

1. Chronic Heart Failure (HFrEF)

In patients with Heart Failure with reduced Ejection Fraction (HFrEF), ACE inhibitors are a Class I recommendation. They improve survival and reduce hospitalizations by:

• Reducing Preload and Afterload: Lowering the pressure the heart must pump against and the volume it must handle.

• Inhibiting Remodeling: They prevent the "deleterious remodeling" (stretching and thickening of heart tissue) that occurs after injury, effectively keeping the heart's shape and function intact.

Reference laboratories are the backbone of precision medicine. While a local hospital lab focuses on rapid "STAT" testing (like a 30-minute blood sugar check for an ER patient), a reference lab focuses on complexity and depth.

By 2026, their role has expanded to include:

• Esoteric Testing: Rare genetic markers, complex autoimmune panels, and specialized toxicology that require multi-million dollar equipment.

• Confirmatory Testing: Serving as the "final word" when a screening test (like an initial HIV or rare pathogen screen) comes back positive or inconclusive.

• Public Health Surveillance: Monitoring the spread of new viral variants and tracking antibiotic resistance patterns across large populations.

The most famous hallmark of Alagille Syndrome is Bile Duct Paucity. In a healthy liver, a network of ducts carries bile to the gallbladder. In ALGS, these ducts are either too few in number or malformed.

This shortage causes bile to accumulate in the liver cells, leading to:

• Cholestasis: A condition where bile flow stops or slows, causing jaundice (yellowing of eyes and skin).

• Severe Pruritus: Intense, debilitating itching caused by the buildup of bile salts in the skin.

• Xanthomas: Fatty, yellow bumps on the skin (often on joints) due to extremely high cholesterol levels.